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Why does letrozole cause joint pain? Joint pain is a common side effect of aromatase inhibitors for postmenopausal breast cancer patients. These powerful drugs that go by the names Arimidex (anastrozole), Femara (letrozole) or Aromasin (exemestane), block the production of aromatase, an enzyme the body uses to generate estrogen.
Is aromatase inhibitor a steroid? In terms of the current inhibitors, anastrozole and letrozole are nonsteroidal, whereas exemestane is a steroidal inhibitor. All AIs are similar in that they inhibit estrogen synthesis by blocking aromatase activity, thereby reducing endogenously synthesized estrogen. However, there are distinct differences among them.
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What are the side effects of stopping tamoxifen? The major symptoms reported when stopping tamoxifen include hot flashes, weight gain, and emotional lability. The women most likely to be affected are those who were premenopausal when they were diagnosed or were post menopausal, but taking HRT when diagnosed.
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